Malaria

Why promising malaria vaccine partly protected kids

Why promising malaria vaccine partly protected kidsWashington D.C, Oct 23 - A recent study has explained the mediocre performance of the world's most advanced malaria vaccine candidate, which offers young children partial protection that wanes with time.


Molecular mechanism that makes malaria parasites drug-resistant identified

Molecular mechanism that makes malaria parasites drug-resistant identifiedWashington, Apr 18 - A team of researchers has made key malarial drug-resistance finding.

Artemisinins are powerful drugs that have the most rapid action of all current drugs against Plasmodium falciparum, the parasite species that causes the most dangerous form of malaria. Artemisinin combination therapies (ACTs) are now standard treatment worldwide for P. falciparum malaria.


Study linking malaria transmission, mosquitoes` sexual biology may yield new target for control

MalariaWashington, Feb 27 - A new study has revealed that malaria transmission is linked to mosquitoes' sexual biology, which can lead to new methods of disease control, particularly in regions hardest hit by it.

Researchers at Harvard T. H. Chan School of Public Health and University of Perugia, Italy found that Anopheles mosquitoes' reproductive traits evolved along with their capacity to transmit the Plasmodium parasite that causes malaria.


Here's how mild reduction in food intake can protect against cerebral malaria

Here's how mild reduction in food intake can protect against cerebral malariaWashington, Jan 31 - A team of scientists has identified two molecular pathways that can lead to new therapeutic targets for cerebral malaria and also, discovered a novel link between food intake during the early stages of infection and the outcome of the disease.


How malaria-spreading mosquitoes can sense you're at home ready to bite

How malaria-spreading mosquitoes can sense you're at home ready to biteWashington, Jan 23 - A new study has revealed that malaria-spreading mosquitoes require minute changes in concentrations of exhaled carbon dioxide to know whether you are at home or not, which then triggers them to land on human skin.


New molecules identified to fight malaria parasite

New molecules identified to fight malaria parasite London, Dec 11 - A team of researchers have identified a family of efficient and selective molecules known as borrelidin which can fight the parasite Plasmodium, causal agent of malaria.

The study conducted at Institute for Research in Biomedicine (IRB Barcelona) described two derivatives of borrelidin that completely remove the parasite load from mice and confer immunological memory to fight future infections.


Scientists close in on malaria's Achilles heel

Scientists close in on malaria's Achilles heelWashington, Sept 10 : A new research has revealed a weakness in the complex life cycle of malaria, which has opened avenues for developing new treatment methods.

Researcher Alexander Maier from Australian National University said that by studying lipid molecules, fats, rather than proteins or DNA, they have opened a new avenue to develop drug treatments for malaria, since the malaria parasites show resistance to all current anti-malarial drugs.


New 'man, machine' system provides for improved malaria diagnosis

New 'man, machine' system provides for improved malaria diagnosisWashington, Aug 22 - Researchers have found a new 'man and machine' decision support system, which provides more effective diagnosis for malaria than the traditional methods.


New hope for curing malaria

New hope for curing malariaWashington, Aug 15 - A new research has developed a fresh computational method to study the function of disease-causing genes with a new discovery of a gene associated with malaria.


Monthly treatment slashes malaria risk in young kids

MalariaWashington, Aug 6 - A new study has found that a year-round preventive drug treatment substantially reduces young children's risk of contracting malaria and poses no serious risk of adverse events.

According to the study, prolonged treatment given from 6 to 24 months of age is safe and effective for young children and a monthly dose of dihydroartemisinin-piperaquine (DP) was the most effective of three anti-malaria drugs.


Scientists identify new malaria vaccine targets

Scientists identify new malaria vaccine targetsWashington, July 31 - A new research has revealed the discovery of previously untested antigens in Kenya, which could help fight malaria.

The researchers from Kenya Medical Research Institute (KEMRI) tested library of proteins from the Plasmodium falciparum parasite with antibodies produced by the immune systems of a group of infected children that measured the proteins the children's immune systems responded to.


First ever malaria vaccines comes closer to reality

malaria vaccines Washington, July 29 : A new study has demonstrated how a first-ever controlled malaria infection clinical trial in Africa has paved a way for the development of anti-malarial drugs and vaccines.

Salim Abdullah, PhD, principal investigator of the study said that they were extremely excited by the good results of this malaria challenge test, which opens up unprecedented opportunity for evaluation of new malaria drugs and vaccines in Africa.


New hope for malaria treatment

New hope for malaria treatmentWashington, July 2 - Researchers have developed a compound that blocks the action of a key ' gatekeeper' enzyme essential for malaria parasite survival.

The researchers have revealed that the compound, called WEHI-916, is the first step toward a new class of antimalarial drugs that could cure and prevent malaria infections caused by all species of the parasite, including those resistant to existing drugs.


Malaria parasite alters host's scent to attract mosquitoes

Malaria parasite alters host's scent to attract mosquitoesWashington, July 1 - A new study has revealed that malaria parasites alter the chemical odor signal of their hosts to attract mosquitoes and better spread their offspring.

According to researchers, malaria-infected mice are more attractive to mosquitoes than uninfected mice and they are the most attractive to these mosquito vectors when the disease is most transmissible.


Bacterial infection in malaria-transmitting mosquito found

Bacterial infection in malaria-transmitting mosquito foundWashington, June 7 - Researchers have found the first evidence of an intercellular bacterial infection in natural populations of two species of Anopheles mosquitoes, the major vectors of malaria in Africa.

The infection, called Wolbachia, has been shown in labs to reduce the incidence of pathogen infections in mosquitoes and has the potential to be used in controlling malaria-transmitting mosquito populations.


Soon, vaccine that stops malaria parasites from multiplying

Soon, vaccine that stops malaria parasites from multiplyingWashington, May 22 - Scientists have identified a substance, or antigen, that generates antibodies that can hinder the ability of malaria parasites to multiply, which may protect against severe malaria infection.


Mobile phone data helps combat malaria more effectively

Mobile phone data helps combat malaria more effectivelyWashington, May 15 - Researchers from the University of Southampton and the National Vector-borne Diseases Control Programme (NVDCP) have used mobile phone data to help combat malaria more effectively in Namibia.


New technique could help control and treat malaria

New technique could help control and treat malariaWashington, May 9 - A new study has revealed that single-cell genomics could provide new insight into the biology of malaria parasites, which can improve treatment and control of the disease.


Targeting Anopheles mosquitoes' sperm could help in fight against malaria

Targeting Anopheles mosquitoes' sperm could help in fight against malariaWashington, March 8 : Researchers have suggested that targeting sperm protection in mosquitoes could help in the fight against malaria.


New class of molecules could help treat malaria

New class of molecules could help treat malariaWashington, March 13 - Researchers have discovered the Achilles heel of the Plasmodium and aims a molecular arrow to destroy it.

The group led by Didier Picard, professor of biology at the Faculty of Sciences of UNIGE, Switzerland, is closely interested in the protein Heat Shock Protein 90 (HSP90), which plays a central role for several factors involved in the life cycle, survival and resistance of the pathogen.


Indian-origin scientist finds way to treat deadly malaria

Indian-origin scientist finds way to treat deadly malariaNew York, Jan 10 - A common but dangerous strain of malaria that hides in the liver, re-emerging years later to trigger new infections and is harder to prevent, diagnose and treat, can soon be treated.


New treatment brings hope for malaria patients

New treatment brings hope for malaria patientsLondon, Dec 23 - In view of increasing cases of malaria treatment failures reported across the globe, scientists have now identified a way to stop malaria parasites from multiplying, raising hope for a new malaria treatment.


New malaria 'blocking' drug raises hopes for new cures

New malaria 'blocking' drug raises hopes for new curesWashington, Dec 23 : In a major breakthrough against fighting malaria, researchers have discovered a new technique to halt the multiplying process of malaria parasites.

A new study shows that blocking the activity of an enzyme, called NMT, in the most common malaria parasite prevents mice from showing symptoms and extends their lifespan.


New drug target brings malaria cure closer to reality

New drug target brings malaria cure closer to realityWashington, Dec 12 - Researchers, who are trying to understand the biology of the malaria parasite, have discovered a potential weakness- low levels of DNA methylation in Plasmodium's genome "that may be critical to the survival of the parasite."

DNA methylation is a biochemical process involving the modification of DNA that plays an important role in development and disease.


Why most life-threatening malaria carrying parasites only infect humans

Why most life-threatening malaria carrying parasites only infect humansWashington, Dec. 3 - Researchers have explained why parasites carrying the deadliest form of malaria only infect humans, asserting that the interaction between a parasite protein, called RH5, and a receptor, called basigin, is essentially required for the invasion of red blood cells.


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