7 DNA regions that influence prostate cancer risk discovered
Submitted by Mohit Joshi on Wed, 07/13/2011 - 10:16
Washington, July 13 : It is well known that men with relatives who have been diagnosed with prostate cancer have an elevated risk of developing this type of cancer.
In 2010, scientists of the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) calculated that this risk rises with the number of affected direct family members and also depends on the relatives'' age at outbreak of the disease.
New drug shows promise in stopping prostate cancer spread to bone
Submitted by Mohit Joshi on Wed, 06/08/2011 - 09:35
Washington, June 8: A new drug designed to target mainly two important pathways linked to the growth and spread of prostate cancer is showing promise to kill tumors that have spread to the bone, a new study has shown.
Researchers enrolled 171 men in the trial with metastatic prostate cancer, in which more than three-quarters of the men enrolled, had seen their cancer spread to the bone.
New targeted therapy for prostate cancer can kill resistant tumor cells
Submitted by Mohit Joshi on Mon, 06/06/2011 - 09:46
Washington, June 6 : Advanced, hormone-resistant prostate cancer can now be killed with the help of a new-targeted therapy that has proved to halt tumor growth in animals.
MRI can help locate prostate cancer recurrence at extremely low PSA levels
Submitted by Mohit Joshi on Sat, 04/30/2011 - 07:44
Washington, April 30 : According to a study recently presented at the Cancer Imaging and Radiation Therapy Symposium in Atlanta, an MRI can locate prostate cancer recurrence at extremely low PSA levels.
Researchers at MD Anderson Cancer Center in Houston evaluated 389 postprostatectomy patients treated between January 2004 and October 2010 to confirm the finding.
Change in PSA level poor predictor of prostate cancer
Submitted by Mohit Joshi on Sun, 04/10/2011 - 05:55
Washington, Apr 10 : Change in PSA levels over time, known as PSA velocity, is a poor predictor of prostate cancer and may lead to many unnecessary biopsies, according to researchers at Memorial Sloan-Kettering Cancer Center.
Several groups, including the National Cancer Center Network and the American Urological Association, recommend that men with high PSA velocity get a biopsy for prostate cancer, even if there are no other indicators that cancer may exist.
Potential driver of some aggressive prostate cancers found
Submitted by Mohit Joshi on Tue, 04/05/2011 - 10:33
Washington, Apr 5: A research team, including an Indian-origin scientist, has found that the mutations of a gene called KRAS, which is known to play a role in numerous cancers, may drive the aggressive spread of a rare subset of prostate cancers.
New tool opens alternate door to prostate cancer diagnosis
Submitted by Mohit Joshi on Sun, 04/03/2011 - 08:53
Washington, April 03 : A new study has suggested that it may not be necessary to look for tumors directly in patients with prostate cancer — analyzing non-tumor tissue may be an effective option.
"A biopsy needle does not need to hit a tumor to detect the presence of tumor," said lead researcher Dan Mercola, professor of pathology and laboratory medicine at the University of California at Irvine.
20-year-long study finds prostate cancer screening doesn''t cut death risk
Submitted by Mohit Joshi on Fri, 04/01/2011 - 09:57
London, April 1: A 20-year-long study has found that screening men for prostate cancer does not significantly reduce deaths from the disease, but increases the risk of treating many people unnecessarily.
The findings are based on a trial started in Sweden in 1987 involving 9,026 men aged 50-69 years identified in the National Population Register.
Change in PSA level poor predictor of prostate cancer
Submitted by Mohit Joshi on Fri, 02/25/2011 - 10:48
Washington, Feb 25: Change in PSA levels over time, known as PSA velocity, is a poor predictor of prostate cancer and may lead to many unnecessary biopsies, according to researchers at Memorial Sloan-Kettering Cancer Center.
Dogs can ‘sniff out’ prostate cancer accurately from urine sample
Submitted by Mohit Joshi on Tue, 02/08/2011 - 06:45
Washington, Feb 8: Researchers have found that some dogs can be trained to accurately sniff out chemicals released in urine that are associated with prostate cancer (PCa).
According to Jean-Nicolas Cornu and colleagues, a trained dog was able to identify volatile compounds (VOCs) that are cancer biomarkers with significant accuracy that could help with prostate cancer diagnosis.
Molecular predictor of metastatic prostate cancer identified
Submitted by Mohit Joshi on Thu, 02/03/2011 - 10:35
London, Feb 03: Researchers at Dana-Farber Cancer Institute have indicated that prostate tumors that carry a "signature" of four molecular markers have the potential to become dangerously metastatic if not treated aggressively.
Protein that protects against prostate cancer discovered
Submitted by Mohit Joshi on Tue, 02/01/2011 - 10:43
Washington, Feb 01: Scientists have identified an important protein, produced naturally inside cells, that appears to suppress the growth of prostate cancer cells in the laboratory.
The findings offer promising leads for research towards new treatments.
Exercise can help slash prostate cancer risk in men
Submitted by Mohit Joshi on Thu, 01/06/2011 - 10:40
London, Jan 6 - Regular exercise can help men with prostate cancer halve their risk of dying from the disease, a British study has found.
The study found that physical activity was linked to a lower risk of dying prematurely from any cause, and in particular from the disease.
Exercise ‘cuts death risk for men with prostate cancer’
Submitted by Mohit Joshi on Thu, 01/06/2011 - 05:12
Washington, Jan 6: Physical activity is associated with a lower risk of overall mortality and of death due to prostate cancer, a new study has found.
Researchers at the Harvard School of Public Health and University of California, San Francisco also found that men who did more vigorous activity had the lowest risk of dying from the disease.
Researchers look at new treatment for prostate cancer
Submitted by Mohit Joshi on Mon, 11/15/2010 - 09:07
London, Nov 15 - A major discovery could pave the way for new treatments in prostate cancer. Researchers have found that male hormones play a key role in promoting a specific genetic change that fuels the growth of tumours.
Their study focused on male sex hormones called androgens and their influence on fusing together genes, according to the journal Cancer Research.
Aspirin cuts prostate cancer risk
Submitted by Mohit Joshi on Wed, 10/27/2010 - 08:39
London, Oct 27 : Prostate cancer sufferers can halve their chances of dying by taking aspirin daily.
A 10-year study of 5,275 men with the early stages of disease, conducted by the Texas Southwestern Medical School in Dallas, US, found that aspirin reduced the risk of dying from 10 percent to four percent.
Now, remote sensing to kill prostate cancer
Submitted by Mohit Joshi on Tue, 10/26/2010 - 07:06
London, Oct 26 :Remote sensing is helping a new radiotherapy treatment combat prostate cancer.
The revolutionary technique has already been used on dozens of patients at the Royal Marsden Hospital in London.
Because it only pinpoints cancer cells, it could impart a cutting edge to radiotherapy for thousands of men and save them from the unpleasant side-effects, the Daily Mail reported Tuesday.
Taking aspirin daily ''cuts prostate cancer risk by 30pc’
Submitted by Mohit Joshi on Thu, 08/12/2010 - 15:25
London, Aug 12 : A new research has shown that taking a low dose of aspirin every day can cut the risk of prostate cancer by almost 30 per cent.
According to scientists at the Fred Hutchinson Cancer Research Centre in Seattle, a 75mg tablet taken on a daily basis has a powerful protective effect against the disease.
Asthmatics on steroids face higher prostate cancer risk
Submitted by Mohit Joshi on Mon, 08/09/2010 - 05:57
London, Aug 9 - Men who take steroid tablets or injections for treating severe asthma could face 70 percent higher risk of prostate cancer.
Those who regularly use an inhaler or a bronchodilator to relieve wheezing are 36 percent more at risk, says a new study.
Potential prostate cancer marker uncovered
Submitted by Mohit Joshi on Tue, 08/03/2010 - 14:50
Washington, Aug 3 : A new study by Purdue University-led team has revealed a potential marker for prostate cancer that could be the starting point for less invasive testing and improved diagnosis of the disease.
The team used a new analysis technique to create a profile of the lipids, or fats, found in prostate tissue and discovered a molecular compound that appears to be useful in identifying cancerous and precancerous tissue.
Cell that could be ‘mother’ of all prostate tumours identified
Submitted by Mohit Joshi on Fri, 07/30/2010 - 13:00
Washington, July 30 : New studies have revealed that a type of prostate cell that has been largely ignored by cancer researchers can, in fact, trigger malignant prostate cancer.
Howard Hughes Medical Institute (HHMI) researcher Owen N. Witte and his colleagues at the University of California, Los Angeles (UCLA) found that the somewhat overlooked prostate basal cell could spawn tumours in the prostate gland.
Biomarkers for particularly aggressive prostate cancers discovered
Submitted by Mohit Joshi on Tue, 07/13/2010 - 10:41
Washington, July 13 : Researchers have uncovered a mechanism that determines prostate cancer aggressiveness, providing new targets for diagnosis and treatment.
The study, led by Ze''ev Ronai, at Sanford-Burnham Medical Research Institute (Sanford-Burnham), appears in the journal Cancer Cell.
The research uncovers a protein named Siah2, which initiates a cascade of molecular events that turn a non-malignant tumour into a metastatic neuroendocrine tumour.
Prostate test ‘can predict death risk’
Submitted by Mohit Joshi on Fri, 07/09/2010 - 15:38
Washington, July 9 : Duke University Medical Center researchers have found that men who have a baseline PSA value of 10 or higher the first time they are tested are up to 11 times more likely to die from prostate cancer than are men with lower initial values.
Scientists say the finding supports routine, early prostate-specific antigen (PSA) screening among healthy men with normal life expectancy - a practice several studies have recently questioned.
Prostate cancer risk increases with number of affected family members
Submitted by Mohit Joshi on Sat, 04/24/2010 - 10:31
Washington, Apr 24 : The more of a man''s direct relatives, i. e. brothers and fathers, are affected with prostate cancer, the higher is his personal risk to develop the disease himself, claims a study.
Researchers of the department headed by Kari Hemminki at DKFZ have studied how high is an individual person''s risk in familial prostate cancer.
New approach may help treat breast, prostate cancers
Submitted by Mohit Joshi on Tue, 02/09/2010 - 08:43
Washington, Feb 9 : Loyola University research team led by an Indian-origin researcher claims to have discovered a novel protein that will help in developing treatments for breast cancer, prostate cancer and enlarged hearts.
When activated, the protein called RSK is involved in cell survival, cell proliferation and cell enlargement.
