Jeffrey Lynn Goldblum (born October 22, 1952) is an Academy-Award nominated American actor. He often portrays quirky, intense or eccentric characters. He is also known for his distinctive appearance and his unique, staccato delivery of lines. At 6 feet 4 ½ inches (1.94 m), he is amongst Hollywood's tallest actors.

Shaggy (born October 22, 1968, in Kingston, Jamaica, real name Orville Richard Burrell CD) is a Jamaican reggae singer who takes his nickname from Scooby-Doo's companion, a nickname given to him by his friends, during his teenage years in which his hair bore a similarity to the Scooby Doo character.

Valeria Golino (October 22, 1966) is a Greek Italian film and television actress. She was born in Naples, Italy to an Italian father who was a Germanist and scholar and a Greek mother who was a painter.

Catherine Deneuve (October 22, 1943, in Paris, France), is an Academy Award-nominated French actress.

Michael Desmond Fishman, (born October 22, 1981 in Long Beach, California) is an American actor best known for playing Roseanne Barr and John Goodman's son, D.J. Conner, on the long-running series Roseanne.

Ishibashi Takaaki (born October 22, 1961) is a Japanese owarai artist, singer and actor. Born in Itabashi, Tokyo Prefecture, Ishibashi attended Teikyo Junior & Senor High School and is best known as a member of Tunnels with his partner Noritake Kinashi.

Amanda Coetzer (born October 22, 1971 in Hoopstad, South Africa) is a former professional tennis player from South Africa.

John Wesley Harding (b. 22 October 1965) is a folk/pop singer-songwriter who has called his style of music "folk noir" and "gangsta folk".