The U.S. researchers claim that prostate cancer therapy has mental impact. ADT or androgen-deprivation therapy is the most common treatment given to the patients suffering from prostate cancer that has spread to the bones or other organs. The researchers claim that this therapy is not free from side effects; this treatment affects mental functioning.  

In the study led by Dr. Christian J. Nelson, from Memorial Sloan-Kettering Cancer Center in New York, the researchers analyzed the data collected from 19 studies linked to ADT involving animals and humans. The researchers found that 47 percent and 69 percent of ADT-treated men suffer from impairment in one or more cognitive areas, most commonly in processes dependent on spatial ability and in high-order "executive functioning" abilities such as the ability to multi-task.

The researchers found that most of the studies looking at the effects of ADT on cognition were small in size with contrasting results. During research, the researchers found that some studies claim that ADT leads to improved verbal memory functioning. The researchers urged that the studies on larger scale should be conducted to determine the effect of hormone therapy on mental functioning. The researchers said that the doctors should educate their patients getting hormone therapy for prostate cancer about the possible side effects of the therapy.