Cancer

Fruit flies’ glow may shed light on cancer prevention

Fruit fliesWashington, January 15: Scientists in the United States have discovered that a chemical signalling system — an important anti-oxidant and cancer prevention pathway long recognized in people and other animals — also plays a role in giving fruit flies a longer lifespan.

The chemical signalling system is one of the ways that the body uses to defend itself from toxic assaults and threats like cigarette smoke, diesel exhaust, and dangerous microbes.

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Stem cells behind bone marrow cancer’s resistance to treatment

Cancer Stem CellsWashington, Jan 12: Researchers at the Johns Hopkins Kimmel Cancer Center have discovered that cancer stem cells for multiple myeloma, which affects bone marrow and other bone tissues, have many properties similar to normal stem cells, thus making the bone marrow cancer resistant to chemotherapy and other treatments.

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Protein that helps pancreatic cancer cells evade immune system identified

Washington, Jan 11: Researchers at Jefferson’s Kimmel Cancer Center in Philadelphia, have found that a protein that helps pancreatic cancer cells evade the immune system.

The protein, the researchers state, produced by metastatic cancer cells in the lymph nodes of patients with pancreatic cancer, do this by destroying the T-cells.

This protein called IDO (indolamine 2’3 dioxygenase) also aids in preventing a woman’s body from rejecting a foetus. It prevents the pancreatic cancer cells from being detected by the immune system by allowing them to spread in the body.

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Eating healthy and better is now just a click away!

Washington, Jan 10: Eating healthy and better is now just a click away!The biggest problem encountered by people going for a healthy diet was to chuck a lot of things they liked eating. But this has now been removed by a new Web site from the University of Michigan Comprehensive Cancer Center that offers healthy and delicious recipes searchable by the ingredients one likes.

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Molecules that could halt breast cancer spread identified

Breast Cancer SymptomsLondon, Jan 10: Scientists have identified a handful of tiny ribonucleic acid (RNA) molecules that suppress the spread of breast cancer to the lungs and bone.

MicroRNAs are known to stall the activity of entire sets of genes linked to cancer metastasis, which is a process that is responsible for the majority of cancer-related deaths.

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Over 100 genes inactivated in cancer cells identified

Washington, January 8: Cancer CellsCarnegie Mellon University researchers have found more than 100 genes that have an abnormal pattern of activation in cancer cells.

Ziv Bar-Joseph, a computational biologist at the university, says that his team used computational biology techniques for identifying these genes.

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Racial differences still prevail in cancer care

Washington, Jan 7: Researchers at the Yale University School of Medicine in New Haven, Connecticut have found that despite efforts in the last 10 years to mitigate cancer treatment disparities, black patients are significantly less likely than white patients to receive therapy for various types of cancer.

Researchers found that the efforts to close treatment gaps initiated in the 1990s have had little impact.

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Key trigger for potent cancer-fighting marine product identified

London, January 5: Scientists at Scripps Institution of Oceanography have made a significant discovery in their marine biomedical laboratories by uncovering a key trigger for a potent cancer-fighting marine product, currently being tested to treat cancer in humans.

The researchers say that their findings may pave the way for new applications of the natural product in treating human diseases.

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3-D model of cancer-promoting enzyme developed

PIK3CA EnzymeWashington, Jan 5: Researchers at the Johns Hopkins Medical Institutions have made a three-dimensional picture of an enzyme often mutated in cancers that may promote the disease after mutation.

The enzyme known as PIK3CA is often mutated in many cancers comprising colon, brain, stomach, breast and lung cancers, making the enzyme more vigorous thus encouraging the cells to divide rapidly than normal, giving rise to cancer.

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Novel anti-cancer strategy targets ‘intercept points’ for cancer cells

Cancer CellWashington, Jan 4 : Scientists at the Emory University have made an advancement in the fight against cancer, by developing an anti-tumour compound called SF1126, which represents a unique strategy of targeting one of the most important "intercept points" for cancer cells.

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4-month course of hormone treatment may delay prostate cancer growth by 8 years

Washington, Jan 3: Researchers at the University of California - San Francisco (UCSF) have suggested that just four months of hormonal therapy could delay prostate cancer growth by up to eight years.

In the study, the researchers found that early short course of hormone treatment given with standard external beam radiation therapy slowed cancer growth by as much as eight years, especially the development of bone metastases, and increased survival in older men with potentially aggressive prostate cancer.

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Antigen gene package to help bring cancer in the firing line

Immune SystemWashington, January 3: Scientists are trying to develop a process to place tumours in the firing line, where they may be attacked by the body’s immune system effectively.

Their endeavour attains significance because tumours are known for changing just enough to stay out of the place where they may be attacked.

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Body abnormalities increase childhood cancer risk

Body abnormalities increase childhood cancer riskWashington, Jan 2: A new study has found that kids with cancer have a higher prevalence of body abnormalities, such as asymmetric lower limbs and curvature of the spine, suggesting that the genetic defect responsible for the abnormality might play a role in the development of the disease.

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Gene seen as target for anti-lung cancer drugs identified

cancer drugsWashington, Jan 1: Scientists have discovered a potential target for anti-lung cancer drugs, by identifying a gene called 14-3-3zeta, which when silenced, doesn’t allow lung cancer cells to survive.

The study was led by Haian Fu, PhD, professor of pharmacology, hematology & oncology at Emory University School of Medicine and Emory Winship Cancer Institute.

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Potential drug target for treatment-resistant prostate cancer found

Washington, Dec 31: Researchers at Jefferson’s Kimmel Cancer Center in Philadelphia have identified the protein that remains active in almost all recurrent prostate cancers, which are resistant to hormone therapy.

Dr. Marja Nevalainen, associate professor of Cancer Biology, has revealed that the protein identified by her team is Stat5, which is key to prostate cancer cell growth.

She believes that this protein might be a specific drug target against an extremely difficult-to-treat cancer.

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Treatment for non-cancer ailments improves survival rates of afflicted patients

Washington, Dec 28: Cancer patientA new study has revealed that treatment for non-cancer health issues, even after the diagnosis of the disease, may improve survival rates of cancer patients.

The study cited that if cancer patients receive specialist treatment for often ignored non-cancer health issues, it might result in a prolonged survival rate.

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Scientists zero in on inflammation and cancer link

Washington, December 28: Scientists following a cancer-targeting molecule called TRAIL have established a link between inflammation and cancer susceptibility through this receptor.

Dr. Wafik S. El-Deiry, a researcher at the University of Pennsylvania School of Medicine, engineered mice to render them without the TRAIL receptor on their cells.

He and his colleagues then exposed mice to radiation so that the subjects would develop chronic pneumonia.

The researcher observed that the mice had not only developed pneumonia but tumours also.

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Exposure to environmental factors may influence testicular cancer risk

Testicular CancerWashington, Dec 26 : A recent study has revealed that exposure to environmental factors in early life may influence the risk of testicular cancer.

The study led by Dr. Charlotte Myrup, of Statens Serum Institute in Copenhagen, Denmark evaluated the occurrence of testicular cancer among first- and second- generation immigrants to Denmark and residents of Danish ancestry.

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Gold nanoparticles may make cancer diagnosis faster, less invasive

London, Dec 24: A study on mice has suggested that gold nanoparticles may make diagnosis of cancer faster and less invasive.

The researchers have shown that by using tiny gold particles embedded with dyes, they could identify tumours under the skin of a living animal, which may lead to earlier detection of cancer.

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Light-activated platinum compound 80 times more powerful than similar cancer treatments

cancer-treatmentWashington, Dec 22: Researchers have found a new light-activated platinum-based compound is up to 80 times more powerful than other platinum-based anti-cancer drugs, and can use ‘light activation’ to kill cancer cells in much more targeted way than similar treatments.

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About 7.6 Million Cancer Deaths in 2007: Study - A Study Report

Washington: About 7.6 million people would die of cancer and more than 12 million people will receive cancer diagnoses.

Global Cancer Facts and Figures 2007 were published by American Cancer Society.

ACS report, based on data compiled by International Research on Cancer (IARC), reveals the disparities in how cancer affects the developed and developing world

Cancer infection is three times higher in developing nations than the developed ones, said report.

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Here’s why we don’t get cancer all the time

Washington, Dec 20: The process of our body to replace the worn-out cells might not be that efficient, but according to a study, it is a defence mechanism against cancer.

Having the neighbouring cell just split into two identical daughter cells would seem to be the simplest way to keep bodies from falling apart. However, according to John W. Pepper of The University of Arizona in Tucson, who led the study, that would be a recipe for uncontrolled growth.

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New method trains immune system to deliver cancer-killing virus

New method trains immune system to deliver cancer-killing virusLondon, December 19: An international team of researchers led by Mayo Clinic has come up with a method to exploit the body’s own cells and a virus to destroy cancer cells that spread from primary tumours to other parts of the body through the lymphatic system.

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Robotic surgery effective in removal of cancer involving the tonsils

Washington, December 18: Researchers at the University of Pennsylvania, Philadelphia, say that a new robotic surgical technique called transoral robotic surgery (TORS) has shown some promise for the removal of cancer involving the tonsil region.

A research team led by Dr. Gregory S. Weinstein carried out tests to check the feasibility of the new technique, involving 27 patients undergoing radical tonsillectomy for cancer between May 2005 and April 2007.

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