Dr. Sood Develops Cure For Ovarian Cancer

Dr. Anil Sood, an Indian-origin researcher and a Professor of Gynecologic Oncology and Cancer Biology in the M. D. Anderson Cancer Center, has developed a protein interleukin-8(IL-8) that helps in the treatment of ovarian cancer.

Sood has found out a short interfering RNA (siRNA) product that slashes IL-8 expression, and decreases the size of the tumor by attacking blood supply.

Sood said, “The protein IL-8 is a potential therapeutic target in ovarian cancer.”

The report also showed that high IL-8 expression in tumors is linked with advanced tumour stage and earlier death for ovarian cancer patients.

“This comprehensive analysis - with human data, animal data and lab experiments to highlight the molecular mechanisms involved - helps us develop the new targets needed for a more effective approach against ovarian cancer,” Sood said.

Interleukin-8 is over expressed in different cancer types and has earlier been shown to encourage tumour growth, new blood vessel growth called angiogenesis, and metastasis, the spread of cancer to other organs.

“In the long run, this research will have applications in other cancers as well,” Sood said.

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