Researchers Found Gene Linked To Higher Gout Risk
The UK researchers have identified a gene variant linked to higher gout risk.
The scientists at the MRC Human Genetics Unit in Edinburgh have noticed a variation in the SLC2A gene that makes it more difficult for the body to take away uric acid from the blood and therefore raising the risk of having ‚Äėgout.‚Äô
Lead scientist Prof Alan Wright said, ‚ÄúThe gene is a key player in determining the efficiency of uric acid transport across the membranes of the kidney.‚ÄĚ
‚ÄúSome people will have higher or lower risk of gout depending on the form of the gene they inherited. This discovery may allow better diagnostic tools for gout to be developed,‚ÄĚ co-researcher Harry Campbell added.
The study researchers came to the decision after they accomplished genetic analysis of more than 12,000 people. They found out that the gene variant increases the risk.
The study findings have been published in the journal ‚ÄúNature Genetics.‚ÄĚ
The researchers say that the recent discovery may help them in discovering better diagnostics and new treatments for this common and terrible situation.
According to the researchers, the ‚ÄėSLC2A‚Äô gene and the protein it controls might be treated by new gout drugs in the future. Currently, drug treatment for patients is limited.
Dr. Andrew Bamji, the President of the British Society for Rheumatology, suggested that too many sugary soft drinks could trigger gout.
‚ÄúIt appears that this gene also plays a role in the control of levels of fructose sugar in the body, which would explain the finding that soft drinks were linked to attacks,‚ÄĚ he said.