Washington, Mar 27 : A researchers duo at the University of Rhode Island has revealed how reactive oxygen species (ROS), a type of stress signal, regulate a cancer causing protein, called Src.
The findings may help understand how this protein normally behaves in human cells, and eventually help in designing drugs to target specific cancers.
Doctoral student David J. Kemble and Professor Gongqin Sun in the URI Department of Cell and Molecular Biology are the first to provide a biochemical mechanism describing how tyrosine kinases sense and respond to oxidation.