In a study the researchers at the University of Pennsylvania - School of Medicine (UPSM), Stanley Goldfarb and Ami Patel have pointed out that large amount of calcium intake is dangerous to health. The incidence of milk alkali or the calcium alkali syndrome is spreading in large parts due to the widespread use of calcium and the supplements of vitamin D. The authors have recommended that due to large calcium intake, which is not just milk, the name of milk alkali syndrome changes to calcium alkali.

The syndrome was sprung up in the early of 1900s when at that time the patients took abundant amount of milk and antacids. If this practice will remain the same then it would led to risk of dangerous high levels of calcium developing in the blood, which even cause the kidney failure and high blood pressure.

Earlier when the new ulcer medicines became available the incidence of milk or calcium-alkali syndrome was declined, but in recent study it has again came into existence. Therefore it should be checked again and mainly the patients with bulimia (an eating disorder), transplant recipients, pregnant and postmenopausal women, and other individuals should not face the developing of calcium alkali syndrome which is a highest risk for them.